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KMID : 0359620110230040203
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Journal of Korean Knee Society
2011 Volume.23 No. 4 p.203 ~ p.207
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The Pattern of Use of Oral NSAIDs with or without Co-prescription of Gastroprotective Agent for Arthritic Knee by Korean Practitioners
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Kim Hee-Chun
Lee Myung-Chul
Moon Young-Wan
Seo Seung-Suk
Lee Kwang-Won
Lee Ju-Hong
Choi Choong-Hyeok
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Abstract
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Purpose: The aim of this study was to describe the patterns of use of non-steroidal anti-inflammatory drugs (NSAIDs) for arthritic knees in clinical practice, particularly focusing on the co-prescription of gastroprotective agents for patients with risk factors for adverse gastrointestinal (GI) events.
Materials and Methods: Each cross-sectional cohort was a group of outpatients visiting 111 physicians who had prescribed NSAIDs for the patients' arthritic knees for more than three consecutive months. A self-administered questionnaire was completed by each patient and physician.
Results: Nine hundred and forty five patients (48%) of the whole 1,960 patients belonged to the group with a high or very high risk for NSAID-induced gastropathy determined by northern California Health Maintenance Organization guidelines. Overall, only less than half of the patients were given co-prescription of gastroprotective agents, regardless of the presence or absence of GI symptoms and irrespective of the level of risk for NSAID-induced gastropathy.
Conclusions: The physician prescribing NSAIDs for arthritic knees should monitor any GI symptoms and the patient monitor anylevel for NSAIDinduced gastropathy, and be willing to add gastroprotective agents as necessary in order to prevent serious adverse GI events.
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KEYWORD
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Knee, Arthritis, Non-steroidal anti-inflammatory drugs, Gastroprotective agents, Co-prescription
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